Spike Protein Explained by Inventor of mRNA Technology Dr. Robert Malone


In an interview with Dr. Erin Stair of TrialSite news, Dr. Robert Malone, inventor of mRNA technology, discusses the spike protein in the COVID vaccines (jabs) and his concerns. Dr. Malone is an avid pro-vaxxer; he describes himself as a "true believer."

In this interview, Dr. Malone discusses his experiences with his colleagues and how they have had their concerns dismissed. He also shared this information on TrialSite News in a report he wrote highlighting his concerns and his colleagues' concerns.

"And so I was on a phone call with a Canadian physician that went from like, 10 to midnight. And the gentleman is just pouring his heart out to me about his patients and how every time we file something that's an adverse event, it just gets immediately dismissed without any investigation. And he's telling me about what's happening in Canada from the government. And I'm listening to this, and I just keep having to say to him, there's nothing I can do for you. And I wake up in the morning, and I, and I, like, aha, I know what I can do. And I built this logic structure around bioethics. It was the bioethics of experimental vaccination for COVID. And it was published on trial site news. And, and every red pill metaphor from the matrix keeps getting overused. But this thing is like a red pill. If people that are in denial, read it. Are you walking through the logic? And it just opens up their mind that it's not okay, what's going on. The censorship isn't okay. The gaslighting of people who have symptoms, the censorship on social media."

Here is the information quoted from the TrialSite News article he wrote:

"By way of background, please understand that I am a vaccine specialist and advocate, as well as the original inventor of the mRNA vaccine (and DNA vaccine) core platform technology. But I also have extensive training in bioethics from the University of Maryland, Walter Reed Army Institute of Research, and Harvard Medical School, and advanced clinical development and regulatory affairs are core competencies for me.

"Before examining the bioethical foundations of current policy and practice which underpin experimental COVID vaccine deployment in many in many western nations, allow me to begin by sharing some "real world" first-hand evidence.

"I was on a call with a Canadian primary care physician last week for a couple of hours. He related the story of the six (in his mind) highly unusual clinical cases of post-vaccination adverse events that he has personally observed in his practice involving the vaccination of his patients with the Pfizer mRNA vaccine product. Keep in mind that it was Canadian physicians – acting of their own accord – who filed the FOIA to gain access to the Pfizer vaccine IND (see https://trialsitenews.com/did-pfizer-fail-to-perform-industry-standard-animal-testing-prior-to-initiation-of-mrna-clinical-trials/)."

"What was most alarming to me was that my clinical primary practice physician colleague told me that each of these cases were reported as per the proper channels in Canada, and each was summarily determined to not be vaccine-related by the authorities without significant investigation. Furthermore, he reported to me that any practicing physician in Canada who goes public with concerns about vaccine safety is subjected to a storm of derision from academic physicians and potential termination of employment (state-controlled socialized medicine) and loss of license to practice."

Dr. Malone also mentions the trusted news initiative, and I want to include a quote from that.

"So this is one of these things that came to me from other dogs, is the trusted news initiative. So trusted news initiative is not a crazy figment of somebody's imagination; you can look it up. And it's a consortium; you can google trusted news initial initiative, BBC, and vaccines. And you're gonna find BBC proudly announcing that they're taking the trusted news initiative Consortium, which includes Facebook and Associated Press and all the usual actors and was designed to combat misinformation in times of crisis and political change. And as of last December, they decided that vaccine disinformation was one of those things. And they were going to clamp down on it. And it feels to many of us like it's coordinated censorship. In fact, it is. It's not; it's not crazy talk."

"I've been swimming in this social media environment for a couple of decades. For me, I mean, it goes back to me interacting on Yahoo stock chat boards at least 20 years ago. So I'm kind of like I say, I put on my big boy pants in the morning. And I'm barely immune to most of this stuff. I mean, there's always haters, and you know, you just delete them, or you don't answer them. Or you know, and you don't talk to the crazies and stuff like that. But yeah, it is. So, you know, when I get fact-checked by PolitiFact and Reuters, and they get it wrong. I do have a certain sense of being threatened. But I try really hard to be well-grounded in the data and to speak from the data and from the science. I don't always get it right. But when I get it wrong, and somebody points it out, I immediately say, Yeah, you're right. I'm wrong."

"And there's so it's not just disinformation coming from social media. The truth is that we're inundated with this information from our public health agencies globally. And I'm sure it's all with the best intent. But, you know, Dr. Fauci was quite clear in the Floyd emails that he has been comfortable substituting his own opinion for facts because he thought he was saying things that would be helpful, but that's not okay. And it's called maizing people's faith in the public health system and a lot of other things. And as you may recall, early on in this outbreak, I made a bunch of statements on LinkedIn that we better make sure if we're going to rush these vaccines, that we get it right. And if we didn't get it, right, we're gonna play right into the storyline, the means of the anti-vaccine crowd. And lo and behold, here we are."

"And I just, I've just come hot off of a meeting with these three insider FDA buddies that I occasionally referred to in these various podcasts. And I felt the need to check in with them and say, Okay, guys, you know, that I've said these things. Are we all okay? Am I still on message? You know, I am missing something. So I just needed felt the need to check in with them. And one of them was quite agitated. Because I found myself on Tucker Carlson last night, and his comment was, Tucker is, you know, his mission is to take down the administration. And he didn't have any specifics; he was completely aligned with what I said. As a matter of fact, I was basically serving as a mouthpiece for a lot of their ranks, in what I said, but he just was adamant that I should be interacting with conservative media. But right now, conservative media are the ones that are open. You and I both, you know, do this where we work with the government and do other things, and we must remain agnostic apolitical. Yeah, I can't be. I can't be aligned with this administration or that administration because they'll change. And that's the nature of working with the federal government is check your politics at the door."

Let's examine what Dr. Malone has to say about the spike protein.

"So this question of the activity, the spike really developed after well well into the outbreak. And it was coupled with people asking what was the activity of the virus itself, using cell culture, animal models organoids is a is kind of a new term for a lot of us. These are our, our human-like organs that are grown in a test tube using stealth stem cell technology. And they've been developed, basically, to enable alternatives to animal models and ability to capture data from human tissues without having to do human experiments. So a series of experiments were done, after they initiated the development of the vaccines that asked questions about the toxicity of the virus, how we've been interacting with brain cells, blood-brain barrier, vascular endothelial cells in general, etc. And then as that science developed, people started asking, Well, how much of these things that we are seeing our response are, are due to this part of the virus or that part of the virus and more than the things they focused on was this knob of three things that kinds of sticks out, that we call spike. It's not it's not spike is not like you would see on the color of a fighting dog or something like that. It's not a bunch of sharp things that come out. It's a bunch of little knobs of protein that are what the viruses is to stick to the cells that it wants to infect. And it also has this characteristic, that it changes its shape. As it infects, like a lot of the virus receptors do a lot of the receptor-ligand interactions, the virus first binds in an open conformation to its target, and then it undergoes a change in shape, that helps trigger the ability of the virus to enter the snow. Spike does this. And so there was data started emerging really last fall with human organoids. And with mouse models, and then with other tissue models. And some, some whole animal studies, including a nice one from the Salk Institute, my alma mater that, in fact, despite what writer says, Yes, Spike is cytotoxic. And spike also opens the blood-brain barrier in animal models and in human organoids. And then there's this whole group of things around symptoms, human symptoms, after infection in development of this disease that we call COVID. And the long-term carbon that we call long carbon. And in some of the side effects that people have reported, with the Add no virus-based genetic vaccines first so here in the States, we call it the j&j product. And we found out the j&j product was causing blood clotting. blood clotting is a major problem with the disease. It's one of the core problems. And the vaccine was also causing blood clotting. That's kind of odd. Now we're seeing that the RNA vaccines a different genetic vaccine technology that also expresses the spike protein is triggering some of those same symptoms in some small subset of people.

"And in some small subset of people, they also have clotting problems including these brain clots, which are worrisome, but that's very rare. And I don't want to alert the audience or scare you by I have no interest in spooking everybody and making a big kerfuffle. Some people enjoy that. I don't. These vaccines were they're saving lives. But in some people, they're having these adverse events. And the odd thing is that those adverse events seem to overlap with some of the symptoms of the disease that's caused by the whole virus. And they seem to overlap between the two different genetic technologies that are used for the vaccines. And so, and they overlap with some of the things that we know that spike can do by itself. And so this is one of those, I'm sorry, I'm gonna say it, it looks like a duck, it walks like a duck and quacks like a duck might be a duck in it might be that these known toxicities associated with the wild type spike protein might be also associated with the engineered spike protein that is used as the antigen in these vaccines. And right now, we don't know that's the case for sure. But it kind of looks like it might be.

When we look more closely at the article, "Bioethics of Experimental COVID Vaccine Deployment under EUA: It's time we stop and look at what's going down". that Dr. Malone wrote and had published on TrialSite News, we can see he has legitimate concerns that many are ignoring some important facts regarding these new vaccines (jabs) as well as the importance of freedom to choose what is done with our bodies. He also points out that it is true that humans are now being used in a huge clinical trial study.

"I believe that adult citizens must be allowed free will, the freedom to choose. This is particularly true in the case of clinical research. These mRNA and recombinant adenovirus vaccine products remain experimental at this time. Furthermore, we are supposed to be doing rigorous, fact-based science and medicine. If rigorous and transparent evaluation of vaccine reactogenicity and treatment-emergent post-vaccination adverse events is not done, we (the public health, clinical research and vaccine developer communities) play right into the hands of anti-vaxxer memes and validate many of their arguments. The suppression of information, discussion, and outright censorship concerning these current COVID vaccines which are based on gene therapy technologies cast a bad light on the entire vaccine enterprise. It is my opinion that the adult public can handle information and open discussion. Furthermore, we must fully disclose any and all risks associated with these experimental research products.

"In this context, the adult public are basically research subjects that are not being required to sign informed consent due to EUA waiver. But that does not mean that they do not deserve the full disclosure of risks that one would normally require in an informed consent document for a clinical trial. And now some national authorities are calling on the deployment of EUA vaccines to adolescents and the young, which by definition are not able to directly provide informed consent to participate in clinical research – written or otherwise.

"The key point here is that what is being done by suppressing open disclosure and debate concerning the profile of adverse events associated with these vaccines violates fundamental bioethical principles for clinical research. This goes back to the Geneva convention and the Helsinki declaration. See https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects/. There must be informed consent for experimentation on human subjects. The human subjects – you, me, and the citizens of these countries – must be informed of risks. As a community, we have already had a discussion and made our decision – we cannot compel prisoners, military recruits, or any other population of humans to participate in a clinical research study. For example, see the Belmont report, which provided the rationale for US federal law Code of Federal Regulations 45 CFR 46 (subpart A), referred to as "The Federal Policy for the Protection of Human Subjects" (also known as the "Common Rule")."

In the below video interview, Dr. Malone discusses anti-body dependent enhancement and that the vaccine causes the virus to become more infective in those who have had the vaccine than those who have not been vaccinated. In addition, he discusses how the Pfizer vaccine is causing the most problems in this regard.


Senator Ron Johnson who is pro-vaccine, speaks with families who are also pro-vaccine, who have had severe reactions, discussing the way they have been treated by the doctors and others in the scientific and trial community.

"A lot of people think of it as a respiratory disease, but it's really a vascular disease," says Assistant Research Professor Uri Manor, who is co-senior author of the study. "That could explain why some people have strokes, and why some people have issues in other parts of the body. The commonality between them is that they all have vascular underpinnings."

…the paper provides clear confirmation and a detailed explanation of the mechanism through which the protein damages vascular cells for the first time.

In the new study, the researchers created a "pseudovirus" that was surrounded by SARS-CoV-2 classic crown of spike proteins, but did not contain any actual virus. Exposure to this pseudovirus resulted in damage to the lungs and arteries of an animal model—proving that the spike protein alone was enough to cause disease. Tissue samples showed inflammation in endothelial cells lining the pulmonary artery walls.

The team then replicated this process in the lab, exposing healthy endothelial cells (which line arteries) to the spike protein. They showed that the spike protein damaged the cells by binding ACE2. This binding disrupted ACE2's molecular signaling to mitochondria (organelles that generate energy for cells), causing the mitochondria to become damaged and fragmented.

Previous studies have shown a similar effect when cells were exposed to the SARS-CoV-2 virus, but this is the first study to show that the damage occurs when cells are exposed to the spike protein on its own.


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  • This commment is unpublished.
    Franz · 1 months ago
    Great work on this Peggy! I'll be adding my article on the WHO whistleblower tomorrow. A one-two punch to the pharma phreaks.
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